Structure of PDB 6s07 Chain A Binding Site BS01

Receptor Information
>6s07 Chain A (length=303) Species: 471852 (Thermomonospora curvata DSM 43183) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMPSFDFDIPRRSPQEIAKGMVAIPGGTFRMGGEDPDAFPEDGEGPVRTV
RLSPFLIDRYAVSNRQFAAFVKATGYVTDAERYGWSFVFHAHVAPGTPVM
DAVVPEAPWWVAVPGAYWKAPEGPGSSITDRPNHPVVHVSWNDAVAYATW
AGKRLPTEAEWEMAARGGLDQARYPWGNELTPRGRHRCNIWQGTFPVHDT
GEDGYTGTAPVNAFAPNGYGLYNVAGNVWEWCADWWSADWHATESPATRI
DPRGPETGTARVTKGGSFLCHESYCNRYRVAARTCNTPDSSAAHTGFRCA
ADP
Ligand information
>6s07 Chain C (length=17) Species: 471852 (Thermomonospora curvata DSM 43183) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gATTPLCGPSRASILSG
Receptor-Ligand Complex Structure
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PDB6s07 Structure of formylglycine-generating enzyme in complex with copper and a substrate reveals an acidic pocket for binding and activation of molecular oxygen.
Resolution1.04 Å
Binding residue
(original residue number in PDB)		F38 E40 A79 Y82 W84 F86 V102 P104 W109 W228 Y273 C274 R276 N285 D288 S289 H293
Binding residue
(residue number reindexed from 1)		F39 E41 A80 Y83 W85 F87 V103 P105 W110 W229 Y274 C275 R277 N286 D289 S290 H294
Enzymatic activity
Enzyme Commision number 1.8.3.7: formylglycine-generating enzyme.
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0120147 formylglycine-generating oxidase activity
GO:1903136 cuprous ion binding
Biological Process
GO:0018158 protein oxidation
GO:0043687 post-translational protein modification

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Molecular Function
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Biological Process
External links
PDB RCSB:6s07, PDBe:6s07, PDBj:6s07
PDBsum6s07
PubMed31588272
UniProtD1A7C3|FGE_THECD Formylglycine-generating enzyme (Gene Name=Tcur_4811)

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