Structure of PDB 6rd2 Chain A Binding Site BS01
Receptor Information
>6rd2 Chain A (length=110) Species:
9606
(Homo sapiens) [
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SEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGR
KIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFA
SAMMHALEVL
Ligand information
>6rd2 Chain D (length=5) Species:
32630
(synthetic construct) [
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TEDEL
Receptor-Ligand Complex Structure
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PDB
6rd2
Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Resolution
1.0 Å
Binding residue
(original residue number in PDB)
M14 K22 W23
Binding residue
(residue number reindexed from 1)
M13 K21 W22
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6rd2
,
PDBe:6rd2
,
PDBj:6rd2
PDBsum
6rd2
PubMed
33184177
UniProt
Q8N8S7
|ENAH_HUMAN Protein enabled homolog (Gene Name=ENAH)
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