Structure of PDB 6r9o Chain A Binding Site BS01

Receptor Information
>6r9o Chain A (length=594) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDIQTYTSINKYEVPPAYSRLPLTSDNFDFTPFNNTEYSGLDPDVDNHYT
NAIIQLYRFIPEMFNFVVGCLKDENFETTLLTDLGYLFDMMERSHGKICS
SSNFQASLKSLTDKRQEPQEHLEEYLESLCIESIKRNMPQKFNRFLLSQL
IKEEAQTVNHNITLNQCFGLETEIRTECSCDHYDTTVKLLPSLSISGINK
QNILPYIEYAMKNVTQKNSETITQECTVKNLPSVLSLELSLLDTEFSNIR
SSKNWLTSEFYGSIIKNKAVLRSTASELKGTSHIFKYELNGYVAKITDNN
NETRLVTYVKKYNPKENCFKWLMFNDYLVVEITEEEALKMTYPWKTPEII
IYCDAEELRKPFFSVDTYSINYDILFRDYFANGIEYKLLTHDEAPKSGTL
VAIDAAFVSLQSELCEIRPKRTALARISIIRGEEGELYGVPFVDDYVVNT
NHIEDYLTRYSGILPGDLDPEKSTKRLVRRNVVYRKVWLLMQLGCVFVGH
GLNNDFKHININVPRNQIRDTAIYFLQGKRYLSLRYLAYVLLGMNIQEGN
HDSIEDAHTALILYKKYLHLKEKAIFEKVLNSVYEEGRAHNFKV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6r9o The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases.
Resolution3.319 Å
Binding residue
(original residue number in PDB)		A912 F913 Y975 S976 N1019 R1045 Y1046 L1047 S1048 L1049
Binding residue
(residue number reindexed from 1)		A406 F407 Y460 S461 N504 R530 Y531 L532 S533 L534
Enzymatic activity
Enzyme Commision number 3.1.13.4: poly(A)-specific ribonuclease.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:6r9o, PDBe:6r9o, PDBj:6r9o
PDBsum6r9o
PubMed31110294
UniProtP53010|PAN2_YEAST PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (Gene Name=PAN2)

[Back to BioLiP]