Structure of PDB 6r9m Chain A Binding Site BS01

Receptor Information
>6r9m Chain A (length=600) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TSDIQTYTSINKYEVPPAYSRLPLTSDNFDFTPFNNTEYSGLDPDVDNHY
TNAIIQLYRFIPEMFNFVVGCLKDENFETTLLTDLGYLFDMMERSHGKIC
SSSNFQASLKSLTDKREPQEHLEEYLESLCIESIKRNMPQKFNRFLLSQL
IKEEAQTVNHNITLNQCFGLETEIRTECSCDHYDTTVKLLPSLSISGINK
TVIKQLGQNILPYIEYAMKNVTQKNSTQECTVKNLPSVLSLELSLLDTEF
SNIRSSKNWLTSEFYGSIIKNKAVLRSTASELKGTSHIFKYELNGYVAKI
TDNNNETRLVTYVKKYNPKENCFKWLMFNDYLVVEITEEEALKMTYPWKT
PEIIIYCDAEELRKPFFSVDTYSINYDILFRDYFANGREYKLLTHDEAPK
SGTLVAIDAAFVSLQSELCEIIRPKRTALARISIIRGEEGELYGVPFVDD
YVVNTNHIEDYLTRYSGILPGDLDPEKSTKRLVRRNVVYRKVWLLMQLGC
VFVGHGLNNDFKHININVPRNQIRDTAIYFLQGKRYLSLRYLAYVLLGMN
IQEGNHDSIEDAHTALILYKKYLHLKEKAIFEKVLNSVYEEGRAHNFKVP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6r9m The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases.
Resolution3.329 Å
Binding residue
(original residue number in PDB)		D910 F913 L972 Y975 R1045 Y1046 S1048
Binding residue
(residue number reindexed from 1)		D408 F411 L462 Y465 R535 Y536 S538
Enzymatic activity
Enzyme Commision number 3.1.13.4: poly(A)-specific ribonuclease.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:6r9m, PDBe:6r9m, PDBj:6r9m
PDBsum6r9m
PubMed31110294
UniProtP53010|PAN2_YEAST PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (Gene Name=PAN2)

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