Structure of PDB 6r9j Chain A Binding Site BS01

Receptor Information
>6r9j Chain A (length=595) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDIQTYTSINKYEVPPAYSRLPLTSTDNFDFTPFNNTEYSGLDPDVDNHY
TNAIIQLYRFIPEMFNFVVGCLKDENFETTLLTDLGYLFDMMERSHGKIC
SSSNFQASLKSLTDKPQEHLEEYLESLCIESIKRNMPQKFNRFLLSQLIK
EEAQTVNHNITLNQCFGLETEIRTECSCDHYDTTVKLLPSLSISGINKTV
IKQLQNILPYIEYAMKNVTQKNSETITQECTVKNLPSVLSLELSLLDTEF
SNIRSSKNWLTSEFYGSIIKNKAVLRSTASELKGTSHIFKYELNGYVAKI
TDNNNETRLVTYVKKYNPKENCFKWLMFNDYLVVEITEEEALKMTYPWKT
PEIIIYCDAEELRKPFFSVDTYSINYDILFRDYARREYKLLTHDEAPKSG
TLVAIDAAFVSLQSELCEPKRTALARISIIRGEEGELYGVPFVDDYVVNT
NHIEDYLTRYSGILPGDLDPEKSTKRLVRRNVVYRKVWLLMQLGCVFVGH
GLNNDFKHININVPRNQIRDTAIYFLQGKRYLSLRYLAYVLLGMNIQEGN
HDSIEDAHTALILYKKYLHLKEKAIFEKVLNSVYEEGRAHNFKVP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6r9j The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases.
Resolution3.326 Å
Binding residue
(original residue number in PDB)		D910 F913 L972 Y975 H1015 N1019 R1045 Y1046 S1048 L1049
Binding residue
(residue number reindexed from 1)		D406 F409 L457 Y460 H500 N504 R530 Y531 S533 L534
Enzymatic activity
Enzyme Commision number 3.1.13.4: poly(A)-specific ribonuclease.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:6r9j, PDBe:6r9j, PDBj:6r9j
PDBsum6r9j
PubMed31110294
UniProtP53010|PAN2_YEAST PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (Gene Name=PAN2)

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