Structure of PDB 6r7v Chain A Binding Site BS01

Receptor Information
>6r7v Chain A (length=307) Species: 28112 (Tannerella forsythia) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RTCGSELNMEQIRRTEPLKYQRITDWENQIKLHSRSVPSSTILIPVVVHV
VYNNSAQNISDAQIISQIQVLNEDFRRMNADQANTPSAFANLAGNANIEF
KLARRDPNGNTTNGITRTSTSTETFSMEMDNVKFSNLGGNNAWNTRRYLN
IWVCNLGDDLLGYAQFPFEFQTKPNTDGVVIHYKHFGRDGSAESPYDKGR
TATHAVGHWLDLRHIWGDDGGSCSGTDNIADTPNQGGYNEGCPSFPKTDH
CTNTSPGVMFMNYMDYTYDACMNLFTKGQVERMRSLFDTQTGIRREMQIY
ANELTNP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6r7v Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6r7v Structure-based mechanism of cysteine-switch latency and of catalysis by pappalysin-family metallopeptidases.
Resolution1.4 Å
Binding residue
(original residue number in PDB)		W236 D239 S242 Q255 G256
Binding residue
(residue number reindexed from 1)		W216 D219 S222 Q235 G236
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008237 metallopeptidase activity

View graph for
Molecular Function
External links
PDB RCSB:6r7v, PDBe:6r7v, PDBj:6r7v
PDBsum6r7v
PubMed31949901
UniProtG8ULV1

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