Structure of PDB 6r6a Chain A Binding Site BS01

Receptor Information
>6r6a Chain A (length=345) Species: 178876 (Cryptococcus neoformans var. grubii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATGTVSLTDVGLDASYAGQVSIGTPAQDFLVIMDSGSSDLWVAGSTCTEN
FCKQTYTFDTSTSSSFITSSEAFNITYGSGDADGTLGTDTVSMAGFTVSD
QTFGVVTSTSANLISYPLSGLMGLAWKSIASSGATPFWQTLAASGDWDSP
EMGVYLKRYRGDNTASQIETDGGQILKGGLNTSLYNGSVNYISIDESEKD
YWRIPLEAMVIQGNSVSIASNPSCAIDTGTTLIGVPSQTANRIYSQIAGA
EALSASSGYEGYYQYPCDTEVTVSLQFGGMSYSISNADMNLGSFTRDTSM
CTGAFFAMDMSSRSPVQWIVGASFIKNVYTAFRYNPAAIGFAELV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6r6a Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		D40 G42 T82 Y83 G84 S85 Y207 D238 G240 T241 T242 M321 I330
Binding residue
(residue number reindexed from 1)		D34 G36 T76 Y77 G78 S79 Y201 D227 G229 T230 T231 M310 I319
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6r6a, PDBe:6r6a, PDBj:6r6a
PDBsum6r6a
PubMed34006103
UniProtJ9VS02

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