Structure of PDB 6r00 Chain A Binding Site BS01

Receptor Information
>6r00 Chain A (length=384) Species: 72120 (Omphalotus olearius) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKAGSLTIVGTGIESIGQMTLQALSYIEAAAKVFYCVIDPATEAFILTKN
KNCVDLYQYYDNGKSRLNTYTQMSELMVREVRKGLDVVGVFYGHPGVFVN
PSHRALAIAKSEGYRARMLPGVSAEDCLFADLCIDPSNPGCLTYEASDFL
IRDRPVSIHSHLVLFQVGCVGIADFNFTGFDNNKFGVLVDRLEQEYGAEH
PVVHYIAAMMPHQDPVTDKYTVAQLREPEIAKRVGGVSTFYIPPKARKAS
NLDIIRRLELLPAGQVPDKKARIYPANQWEPDVPEVEPYRPSDQAAIAQL
ADHAPPEQYQPLATSKAMSDVMTKLALDPKALADYKADHRAFAQSVPDLT
PQERAALELGDSWAIRCAMKNMPSSLLDAARESG
Ligand information
>6r00 Chain B (length=14) Species: 72120 (Omphalotus olearius) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
FPWVIVFGVIGVIG
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6r00 Substrate Plasticity of a Fungal Peptide alpha-N-Methyltransferase.
Resolution1.74 Å
Binding residue
(original residue number in PDB)		I44 Y63 Y66 S71 R72 L73 Y76 Y98 F104 V105 N106 P107 E151 R158 Q172 G174 I178 A179 T184 G185 F186 G242
Binding residue
(residue number reindexed from 1)		I38 Y57 Y60 S65 R66 L67 Y70 Y92 F98 V99 N100 P101 E145 R152 Q166 G168 I172 A173 T178 G179 F180 G236
Enzymatic activity
Enzyme Commision number 2.1.1.-
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
Biological Process
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:6r00, PDBe:6r00, PDBj:6r00
PDBsum6r00
PubMed32491837
UniProtA0A2R2JFI5|OPHMA_OMPOL Methyltransferase/ribosomally synthesized cyclic peptide omphalotin A precursor ophMA (Gene Name=ophMA)

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