Structure of PDB 6qzj Chain A Binding Site BS01

Receptor Information
>6qzj Chain A (length=245) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVH
VAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSL
FYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQ
LCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPP
RIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAYLGGIIYLVFIGS
Ligand information
Ligand IDGOL
InChIInChI=1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2
InChIKeyPEDCQBHIVMGVHV-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0C(C(CO)O)O
ACDLabs 12.01
CACTVS 3.370		OCC(O)CO
FormulaC3 H8 O3
NameGLYCEROL;
GLYCERIN;
PROPANE-1,2,3-TRIOL
ChEMBLCHEMBL692
DrugBankDB09462
ZINCZINC000000895048
PDB chain6qzj Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6qzj Structural Basis for Glycerol Efflux and Selectivity of Human Aquaporin 7.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		V82 G90
Binding residue
(residue number reindexed from 1)		V49 G57
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015267 channel activity
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6qzj, PDBe:6qzj, PDBj:6qzj
PDBsum6qzj
PubMed31831212
UniProtO14520|AQP7_HUMAN Aquaporin-7 (Gene Name=AQP7)

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