Structure of PDB 6qrz Chain A Binding Site BS01

Receptor Information
>6qrz Chain A (length=274) Species: 330779 (Sulfolobus acidocaldarius DSM 639) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IHKKFKATSVGYDWNTFPMKLYQIGKRLFWDPAKIDFSKDKEDWKKLSKD
EKNYLLNIVSLFMAGEEAVAVDITPLISTMINEGRVEDVIYLEQFAFEEA
KHAEAFRRFCDSLEINDDLTIFTTEYNPWYQKIFYEELPSVMWKLRVDPS
PENLAVAVTTYNLYVEGVAAESGYKTFKHIFNSLNIMPGLSKTVNLIATD
ESRHIAYGTYLITRLIVENGESIYRKAIEQFNKLVGLPFGLTPDFTIENR
KQLVNARLTVIERALKMTPEQVKS
Ligand information
Ligand IDMN3
InChIInChI=1S/Mn/q+3
InChIKeyMMIPFLVOWGHZQD-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Mn+3]
FormulaMn
NameMANGANESE (III) ION
ChEMBL
DrugBank
ZINC
PDB chain6qrz Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6qrz Solving a new R2lox protein structure by microcrystal electron diffraction.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		E79 E112 H115 E214
Binding residue
(residue number reindexed from 1)		E66 E99 H102 E201
Annotation score1
Enzymatic activity
Enzyme Commision number 1.17.4.1: ribonucleoside-diphosphate reductase.
Gene Ontology
Molecular Function
GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0016491 oxidoreductase activity
Biological Process
GO:0009263 deoxyribonucleotide biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6qrz, PDBe:6qrz, PDBj:6qrz
PDBsum6qrz
PubMed31457106
UniProtQ4J6V7

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