Structure of PDB 6qnn Chain A Binding Site BS01

Receptor Information
>6qnn Chain A (length=354) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVI
IDMNDPSNPIRRPISADSAIMNPASKVIALKAGKTLQIFNIEMKSKMKAH
TMTDDVTFWKWISLNTVALVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQ
IINYRTDAKQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAASFA
QFKMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGNQPFPKKAVDVFF
PPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISGET
IFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMA
VRNN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6qnn Clathrin's adaptor interaction sites are repurposed to stabilize microtubules during mitosis.
Resolution2.03 Å
Binding residue
(original residue number in PDB)		H145 L183 V190 S191 Q192 F218 I231 K245
Binding residue
(residue number reindexed from 1)		H143 L181 V188 S189 Q190 F216 I229 K243
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030130 clathrin coat of trans-Golgi network vesicle
GO:0030132 clathrin coat of coated pit

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6qnn, PDBe:6qnn, PDBj:6qnn
PDBsum6qnn
PubMed31932847
UniProtQ00610|CLH1_HUMAN Clathrin heavy chain 1 (Gene Name=CLTC)

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