Structure of PDB 6qmm Chain A Binding Site BS01

Receptor Information
>6qmm Chain A (length=277) Species: 1140 (Synechococcus elongatus PCC 7942 = FACHB-805) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SADAPVWIDEVFEDRVRYGLRGQILWEETSPFQKITIVDTEHYGRGLLLD
DCWMTAERCEVCYHEYLVHPPLTTAASIARVLVIGGGDGGTVREVLRYAE
VEQVDLVEIDGRVVELSQEYLGAIGTAWADPRLNVKIGDGIAFVQTAPDA
SYDVILVDGSGLFNREFYENCRRVLKPGGVFASQAESPDSFLAVHLEMIE
TLSAVFAEAKPYYGWVPMYPSGWWSWLYASDTPGQFQKPQSDRLAAIEPQ
VEIYNRDIHQAAFAQPNFVRRGLSARQ
Ligand information
Ligand IDPUT
InChIInChI=1S/C4H12N2/c5-3-1-2-4-6/h1-6H2
InChIKeyKIDHWZJUCRJVML-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(CCN)CN
ACDLabs 10.04
CACTVS 3.341		NCCCCN
FormulaC4 H12 N2
Name1,4-DIAMINOBUTANE;
PUTRESCINE
ChEMBLCHEMBL46257
DrugBankDB01917
ZINCZINC000005828633
PDB chain6qmm Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6qmm Crystal structure of dimericSynechococcusspermidine synthase with bound polyamine substrate and product.
Resolution2.18 Å
Binding residue
(original residue number in PDB)		M55 G160 Y227
Binding residue
(residue number reindexed from 1)		M54 G159 Y219
Annotation score5
Enzymatic activity
Enzyme Commision number 2.5.1.16: spermidine synthase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004766 spermidine synthase activity
GO:0016740 transferase activity
Biological Process
GO:0006596 polyamine biosynthetic process
GO:0008295 spermidine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6qmm, PDBe:6qmm, PDBj:6qmm
PDBsum6qmm
PubMed30877192
UniProtQ31QK9|SPEE_SYNE7 Polyamine aminopropyltransferase (Gene Name=speE)

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