Structure of PDB 6qcv Chain A Binding Site BS01

Receptor Information
>6qcv Chain A (length=717) Species: 1601067 (Influenza B virus (B/Memphis/13/2003)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMDTFITRNFQTTIIQKAKNTMAEFSEDPELQPAMLFNICVHLEVCYVIS
DMNFLDEEGKAYTAQNLRPQYEVIEGMPRTIAWMVQRSLAQEHGIETPKY
LADLFDYKTKRFIEVGITKGLADDYFWKKKEKLGNSMELMIFSYNQDYSL
SNESSLDEEGKGRVLSRLTELQAELSLKNLWQVLIGEEDVEKGIDFKLGQ
TISRLRDISVPAGFSNFEGMRSYIDNIDPKGAIERNLARMSPLVSVTPKK
LTWEDLRPIGPHIYNHELPEVPYNAFLLMSDELGLANMTEGKSKKPKTLA
KECLEKYSTLRDQTDPILIMKSEKANENFLWKLWRDCVNTISNEEMSNEL
QKTNYAKWATGDGLTYQKIMKEVAIDDETMCQEEPKIPNKCRVAAWVQTE
MNLLSTLTSKRALDLPEIGPDVAPVEHVGSERRKYFVNEINYCKASTVMM
KYVLFHTSLLNESNASMGKYKVIPITNRVVNEKGESFDMLYGLAVKGQSH
LRGDTDVVTVVTFEFSSTDPRVDSGKWPKYTVFRIGSLFVSGREKSVYLY
CRVNGTNKIQMKWGMEARRCLLQSMQQMEAIVEQESSIQGYDMTKACFKG
DRVNSPKTFSIGTQEGKLVKGSFGKALRVIFTKCLMHYVFGNAQLEGFSA
ESRRLLLLIQALKDRKGPWVFDLEGMYSGIEECISNNPWVIQSAYWFNEW
LGFEKEGSKVLESVDEI
Ligand information
>6qcv Chain R (length=21) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uauaccucugcuucugcuauu
.....................
Receptor-Ligand Complex Structure
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PDB6qcv Structural snapshots of actively transcribing influenza polymerase.
Resolution3.24 Å
Binding residue
(original residue number in PDB)		K374 M473 H506 L507 R508 K564
Binding residue
(residue number reindexed from 1)		K368 M467 H500 L501 R502 K558
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0039523 symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
GO:0039694 viral RNA genome replication
GO:0075526 cap snatching
Cellular Component
GO:0030430 host cell cytoplasm
GO:0042025 host cell nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6qcv, PDBe:6qcv, PDBj:6qcv
PDBsum6qcv
PubMed31160782
UniProtQ5V8Z9

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