Structure of PDB 6qcs Chain A Binding Site BS01

Receptor Information
>6qcs Chain A (length=715) Species: 11520 (Influenza B virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDTFITRNFQTTIIQKAKNTMAEFSEDPELQPAMLFNICVHLEVCYVISD
MNFLDEEGKAYTANLRPQYEVIEGMPRTIAWMVQRSLAQEHGIETPKYLA
DLFDYKTKRFIEVGITKGLADDYFWKKKEKLGNSMELMIFSYNQDYSLSN
ESSLDEEGKGRVLSRLTELQAELSLKNLWQVLIGEEDVEKGIDFKLGQTI
SRLRDISVPAGFSNFEGMRSYIDNIDPKGAIERNLARMSPLVSVTPKKLT
WEDLRPIGPHIYNHELPEVPYNAFLLMSDELGLANMTEGKSKKPKTLAKE
CLEKYSTLRDQTDPILIMKSEKANENFLWKLWRDCVNTISNEEMSNELQK
TNYAKWATGDGLTYQKIMKEVAIDDETMCQEEPKIPNKCRVAAWVQTEMN
LLSTLTSKRALDLPEIGPDVAPVEHVGSERRKYFVNEINYCKASTVMMKY
VLFHTSLLNESNASMGKYKVIPITNRVVNEKGESFDMLYGLAVKGQSHLR
GDTDVVTVVTFEFSSTDPRVDSGKWPKYTVFRIGSLFVSGREKSVYLYCR
VNGTNKIQMKWGMEARRCLLQSMQQMEAIVEQESSIQGYDMTKACFKGDR
VNSPKTFSIGTQEGKLVKGSFGKALRVIFTKCLMHYVFGNAQLEGFSAES
RRLLLLIQALKDRKGPWVFDLEGMYSGIEECISNNPWVIQSAYWFNEWLG
FEKEGSKVLESVDEI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6qcs Structural snapshots of actively transcribing influenza polymerase.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		K330 T366 G369 L370 T371 P391 P394 H506 V513 T515 R558 N560 G561
Binding residue
(residue number reindexed from 1)		K322 T358 G361 L362 T363 P383 P386 H498 V505 T507 R550 N552 G553
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0039523 symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
GO:0039694 viral RNA genome replication
GO:0075526 cap snatching
Cellular Component
GO:0030430 host cell cytoplasm
GO:0042025 host cell nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6qcs, PDBe:6qcs, PDBj:6qcs
PDBsum6qcs
PubMed31160782
UniProtQ5V8Z9

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