Structure of PDB 6pz5 Chain A Binding Site BS01

Receptor Information
>6pz5 Chain A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFHTSVSRPGRGEPRFITVGYVDDTLFVRFDSDAASPREEPRAP
WIEQEGPEHWDRETQICKAKAQTDREDLRTLLRYYNQSEAGSHTLQNMYG
CDVGPDGRLLRGYHQDAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGECVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6pz5 Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation.
Resolution1.53 Å
Binding residue
(original residue number in PDB)
Y7 T24 E45 R62 E63 I66 C67 E76 D77 L81 Y84 Y99 D116 Y123 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 T24 E45 R62 E63 I66 C67 E76 D77 L81 Y84 Y99 D116 Y123 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6pz5, PDBe:6pz5, PDBj:6pz5
PDBsum6pz5
PubMed31740583
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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