Structure of PDB 6pyl Chain A Binding Site BS01

Receptor Information
>6pyl Chain A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFHTSVSRPGRGEPRFITVGYVDDTLFVRFDSDAASPREEPRAP
WIEQEGPEHWDRETQICKAKAQTDREDLRTLLRYYNQSEAGSHTLQNMYG
CDVGPDGRLLRGYHQDAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGECVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>6pyl Chain C (length=10) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
KRWIILGLNK
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6pyl Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation.
Resolution1.52 Å
Binding residue
(original residue number in PDB)		Y7 T24 E45 E63 I66 C67 E76 D77 Y84 Y99 H114 D116 T143 K146 W147 V152 Q155 L156 Y159 E163 W167 Y171
Binding residue
(residue number reindexed from 1)		Y7 T24 E45 E63 I66 C67 E76 D77 Y84 Y99 H114 D116 T143 K146 W147 V152 Q155 L156 Y159 E163 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6pyl, PDBe:6pyl, PDBj:6pyl
PDBsum6pyl
PubMed31740583
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

[Back to BioLiP]