Structure of PDB 6px3 Chain A Binding Site BS01

Receptor Information
>6px3 Chain A (length=96) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGE
Ligand information
>6px3 Chain I (length=145) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tggagaatcccggtgccgaggccgctcaattggtcgtagacagctctagc
accgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgccaaggg
gattactccctagtctccaggcacgtgtcagatatatacatcctg
Receptor-Ligand Complex Structure
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PDB6px3 Nucleosome and ubiquitin position Set2 to methylate H3K36.
Resolution4.1 Å
Binding residue
(original residue number in PDB)		Y41 P43 G44 V46 R49 K56 R63 K64 L65 P66 R69
Binding residue
(residue number reindexed from 1)		Y4 P6 G7 V9 R12 K19 R26 K27 L28 P29 R32
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6px3, PDBe:6px3, PDBj:6px3
PDBsum6px3
PubMed31439846
UniProtP02302|H3C_XENLA Histone H3.3C (Gene Name=h3-5)

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