Structure of PDB 6pt2 Chain A Binding Site BS01

Receptor Information
>6pt2 Chain A (length=397) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TMADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKL
EDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTR
NAYIQKYLRSASSLALAIAITALYSAVCAVGLLGNVLVMFVIVRYTKMKT
ATNIYIFSLALAGALATSTLPFQSADYLMETWPFGELLCKAVLSIDYYSM
FTSIFTLTMMCVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVP
IMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVC
YGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVVAFVVCWAPIHIFVI
VWTLVDIDRRDPLVVAALHLCIALGYINSSLNPVLYAFLDKNFKRCF
Ligand information
Receptor-Ligand Complex Structure
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PDB6pt2 Elucidating the active delta-opioid receptor crystal structure with peptide and small-molecule agonists.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		Q105 D108 W114 Y129 M132 V217 I277 Y308
Binding residue
(residue number reindexed from 1)		Q173 D176 W182 Y197 M200 V285 I345 Y376
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0004985 G protein-coupled opioid receptor activity
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0020037 heme binding
GO:0038046 G protein-coupled enkephalin receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0022900 electron transport chain
Cellular Component
GO:0016020 membrane
GO:0042597 periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6pt2, PDBe:6pt2, PDBj:6pt2
PDBsum6pt2
PubMed31807708
UniProtP41143|OPRD_HUMAN Delta-type opioid receptor (Gene Name=OPRD1)

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