Structure of PDB 6ppr Chain A Binding Site BS01

Receptor Information
>6ppr Chain A (length=834) Species: 1772 (Mycolicibacterium smegmatis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVVRLLGPGTGKSSLLVDTAVQHILLTGSARLRTAARAAITARLTVHSYA
FAVLRLSAEQDGIIRELLAGDGWPEQLWPALTTAGFATELRDLMARCTER
GVDPIALQRLGRPEWLAAGRFAQAYEQILGAAELVGAALEALLLDTERNR
IKLLLVDDAQHLDPQAARLVRALALTVIAGDPDQSHPAITLTQSYRCAPE
IASAITGLGQWTGNPQREGTVTVRLAASTHAEGTMIADALRRAHLVDGIP
WSQMAVIVRSVPRVGTALARALTAAGVPVQDDVPVGRQPAAAALLTVLDV
TATGHLDADSAVALLTGPIGRVDPVTLRQLRRALRRADGSQPPRDFGDLL
VDAIEREPKGLSAEHARTLRRLRAVLTAARRDPRYTLWQAWHASGLQRRW
LAASERGGSVGAQADRDLDAVTTLFDVADQYVLRGLVDHVAVAVLSVHGA
LAGEWDFVVIAGVQEGLWPNMIPRGGVLGTQHLVDVLLVAEERRLLMAAM
GRARTRVMITAVDLLPSPFCAEISAWATEPPLVAPRVLAPSALVGRLRAV
VCAPDARACAAAQLARLAAAGVPGADPSQWHAMTSLTTEEPLWSEPGHVV
TLSPSTLQMLTDCPLRWLLERHGGDDGRDVRSTVGSLVHALVSEPGKTES
QLVNELEKVWDDLPYDAKWYSDNELARHRAMLETFTRWREDTRRQLTEVA
TEIPVEGIVVEPGVRVRGRLDRLERDEAGRLVVVALKTGKSPVTKDDAQN
HAQLAMYQLAVAAGLGDEPGGGKLVYLGKAGATEREQDPLTPDKRAEWLE
TVGEAAAATAGPRFVARVNNGCANCPVRSSCPAQ
Ligand information
Receptor-Ligand Complex Structure
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PDB6ppr Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
S799 R815 R916 R918 K936 G938 K939 S940 T943 K944 Y956
Binding residue
(residue number reindexed from 1)
S605 R621 R717 R719 K737 G739 K740 S741 T744 K745 Y757
Enzymatic activity
Enzyme Commision number 5.6.2.4: DNA 3'-5' helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016853 isomerase activity
GO:0043138 3'-5' DNA helicase activity
Biological Process
GO:0000725 recombinational repair
GO:0006281 DNA repair
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0005829 cytosol
GO:0033202 DNA helicase complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6ppr, PDBe:6ppr, PDBj:6ppr
PDBsum6ppr
PubMed31740608
UniProtA0QTR9

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