Structure of PDB 6pgq Chain A Binding Site BS01

Receptor Information
>6pgq Chain A (length=473) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFP
QVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVR
YNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALM
FNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDL
IKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLP
TFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKP
LGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVI
NAASGRQTVDEALKDAQTNAAAEFLYVVGRKKMMDAQYKCYDRMQQLPAY
QGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEK
GVWFKHPENNRTWSNYTMCNAFT
Ligand information
Receptor-Ligand Complex Structure
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PDB6pgq Calcitonin Receptor N-Glycosylation Enhances Peptide Hormone Affinity by Controlling Receptor Dynamics.
Resolution2.85 Å
Binding residue
(original residue number in PDB)		D77 W79 F99 D101 H121 E123 N124 R126 W128 S129 N135
Binding residue
(residue number reindexed from 1)		D412 W414 F434 D436 H456 E458 N459 R461 W463 S464 N470
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0015144 carbohydrate transmembrane transporter activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0008643 carbohydrate transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6pgq, PDBe:6pgq, PDBj:6pgq
PDBsum6pgq
PubMed32035902
UniProtP30988|CALCR_HUMAN Calcitonin receptor (Gene Name=CALCR)

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