Structure of PDB 6pag Chain A Binding Site BS01
Receptor Information
>6pag Chain A (length=277) Species:
9606
(Homo sapiens) [
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SHSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPRGEPRAPW
VEQEGPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSEDGSHTLQRMSGC
DLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAAR
AAEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATL
RCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPS
GQEQRYTCHMQHEGLQEPLTLSWEPSS
Ligand information
>6pag Chain C (length=9) Species:
32630
(synthetic construct) [
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RYRPGTVAL
Receptor-Ligand Complex Structure
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PDB
6pag
Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C.
Resolution
2.501 Å
Binding residue
(original residue number in PDB)
Y7 D9 Y59 R62 E63 K66 Y67 Q70 V76 S77 N80 Y84 D114 T143 A150 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y6 D8 Y58 R61 E62 K65 Y66 Q69 V75 S76 N79 Y83 D113 T142 A149 Y158 W166 Y170
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6pag
,
PDBe:6pag
,
PDBj:6pag
PDBsum
6pag
PubMed
33846289
UniProt
P10321
|HLAC_HUMAN HLA class I histocompatibility antigen, C alpha chain (Gene Name=HLA-C)
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