Structure of PDB 6pa1 Chain A Binding Site BS01
Receptor Information
>6pa1 Chain A (length=271) Species:
9606
(Homo sapiens) [
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SHSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPRGEPRAPW
VEQEGPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSEDGSHTLQRMSGC
DLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAAR
AAEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATL
RCWALGFYPAEITLTWQRDGEDQTQETRPAGDGTFQKWAAVVVPSGQEQR
YTCHMQHEGLQEPLTLSWEPS
Ligand information
>6pa1 Chain C (length=9) Species:
32630
(synthetic construct) [
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RYRPGTVAL
Receptor-Ligand Complex Structure
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PDB
6pa1
Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C.
Resolution
3.01 Å
Binding residue
(original residue number in PDB)
Y7 D9 Y59 E63 K66 Y67 Q70 A73 S77 R97 D114 T143 A150 L156 Y159 W167
Binding residue
(residue number reindexed from 1)
Y6 D8 Y58 E62 K65 Y66 Q69 A72 S76 R96 D113 T142 A149 L155 Y158 W166
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6pa1
,
PDBe:6pa1
,
PDBj:6pa1
PDBsum
6pa1
PubMed
33846289
UniProt
P10321
|HLAC_HUMAN HLA class I histocompatibility antigen, C alpha chain (Gene Name=HLA-C)
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