Structure of PDB 6p2s Chain A Binding Site BS01
Receptor Information
>6p2s Chain A (length=275) Species:
9606
(Homo sapiens) [
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GSHSMRYFDTAMSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAP
WIEQEGPEYWDRNTQIFKTNTQTDRCSLRNLRGYYNQSEAGSHTLQSMYG
CDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAA
RVAEQDRAYLEGTCVEWLRRYLENGKDTLERADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>6p2s Chain C (length=9) Species:
11676
(Human immunodeficiency virus 1) [
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AAAKKKYCL
Receptor-Ligand Complex Structure
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PDB
6p2s
ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation.
Resolution
1.65 Å
Binding residue
(original residue number in PDB)
Y7 D9 N63 I66 F67 N70 T73 D74 C76 S77 N80 Y84 S97 Y99 Y116 Y123 T143 W147 Q155 D156 Y159 Y171
Binding residue
(residue number reindexed from 1)
Y7 D9 N63 I66 F67 N70 T73 D74 C76 S77 N80 Y84 S97 Y99 Y116 Y123 T143 W147 Q155 D156 Y159 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6p2s
,
PDBe:6p2s
,
PDBj:6p2s
PDBsum
6p2s
PubMed
31601650
UniProt
P01889
|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)
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