Structure of PDB 6p2c Chain A Binding Site BS01
Receptor Information
>6p2c Chain A (length=275) Species:
9606
(Homo sapiens) [
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GSHSMRYFDTAMSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAP
WIEQEGPEYWDRNTQIFKTNTQTDRCSLRNLRGYYNQSEAGSHTLQSMYG
CDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAA
RVAEQDRAYLEGTCVEWLRRYLENGKDTLERADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>6p2c Chain C (length=9) Species:
11676
(Human immunodeficiency virus 1) [
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AAAKKKYCL
Receptor-Ligand Complex Structure
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PDB
6p2c
ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation.
Resolution
1.396 Å
Binding residue
(original residue number in PDB)
D9 N63 I66 F67 N70 T73 D74 C76 S77 N80 Y84 S97 Y123 T143 W147 V152 Q155 D156 Y159 W167
Binding residue
(residue number reindexed from 1)
D9 N63 I66 F67 N70 T73 D74 C76 S77 N80 Y84 S97 Y123 T143 W147 V152 Q155 D156 Y159 W167
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6p2c
,
PDBe:6p2c
,
PDBj:6p2c
PDBsum
6p2c
PubMed
31601650
UniProt
P01889
|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)
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