Structure of PDB 6oyl Chain A Binding Site BS01

Receptor Information
>6oyl Chain A (length=323) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNV
ITEPIYPEVVHMFAVNMFRTLPPEAAWPHLQLVYEFFLRFLESPDFQPNI
AKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQI
NNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPL
HKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMF
LNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEY
IMSLISDNAAKILPIMFPSLYRN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6oyl A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment.
Resolution3.15 Å
Binding residue
(original residue number in PDB)		H187 Y190 A198 E226 S230 N233 G234 F235 A236
Binding residue
(residue number reindexed from 1)		H133 Y136 A144 E172 S176 N179 G180 F181 A182
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0019888 protein phosphatase regulator activity
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0000159 protein phosphatase type 2A complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6oyl, PDBe:6oyl, PDBj:6oyl
PDBsum6oyl
PubMed32195664
UniProtQ13362|2A5G_HUMAN Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (Gene Name=PPP2R5C)

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