Structure of PDB 6oqy Chain A Binding Site BS01

Receptor Information
>6oqy Chain A (length=237) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHESTFGLMCKMADQ
TLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEG
SIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCL
KFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLL
RLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6oqy Development of the First Low Nanomolar Liver Receptor Homolog-1 Agonist through Structure-guided Design.
Resolution2.23 Å
Binding residue
(original residue number in PDB)		F354 R361 V371 Q374 M375 L531 E534
Binding residue
(residue number reindexed from 1)		F53 R60 V70 Q73 M74 L230 E233
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity

View graph for
Molecular Function
External links
PDB RCSB:6oqy, PDBe:6oqy, PDBj:6oqy
PDBsum6oqy
PubMed31419141
UniProtO00482|NR5A2_HUMAN Nuclear receptor subfamily 5 group A member 2 (Gene Name=NR5A2)

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