Structure of PDB 6ome Chain A Binding Site BS01

Receptor Information
>6ome Chain A (length=499) Species: 272561 (Chlamydia trachomatis D/UW-3/CX) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VVLLYSQASWDQRSKADALVLPFWMKNSKAQEAAVVDEDYKLVYQNALSN
FSGKKGETAFLFGNDHTKEQKIVLLGLGKSEEVSGTTVLEAYAQATTVLR
KAKCKTVNILFPTISQLRFSVEEFLTNLAAGVLSLNYNYPTYHKVDTSLP
FLEKVTVIGIVSKVGDKIFRKEESLFEGVYLTRDLVNTNADEVTPEKLAA
VAKGLAGEFASLDVKILDRKAILKEKMGLLAAVAKGAAVEPRFIVLDYQG
KPKSKDRTVLIGKGVTFDSGGLDLKPGKAMITMKEDMAGAATVLGIFSAL
ASLELPINVTGIIPATENAIGSAAYKMGDVYVGMTGLSVEIGSTDAEGRL
ILADAISYALKYCNPTRIIDFATLTGAMVVSLGESVAGFFANNDVLARDL
AEASSETGEALWRMPLVEKYDQALHSDIADMKNIGSNRAGSITAALFLQR
FLEDNPVAWAHLDIAGTAYHEKEELPYPKYATGFGVRCLIHYMEKFLSK
Ligand information
Ligand IDCO3
InChIInChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
InChIKeyBVKZGUZCCUSVTD-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(=O)([O-])[O-]
ACDLabs 10.04
CACTVS 3.341		[O-]C([O-])=O
FormulaC O3
NameCARBONATE ION
ChEMBL
DrugBankDB14531
ZINC
PDB chain6ome Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6ome Crystal structure of a probable cytosol aminopeptidase (Leucine aminopeptidase, LAP) from Chlamydia trachomatis D/UW-3/Cx
Resolution1.95 Å
Binding residue
(original residue number in PDB)		A346 G348 R349 L374
Binding residue
(residue number reindexed from 1)		A346 G348 R349 L374
Annotation score3
Enzymatic activity
Enzyme Commision number 3.4.11.1: leucyl aminopeptidase.
3.4.11.10: bacterial leucyl aminopeptidase.
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0008233 peptidase activity
GO:0008235 metalloexopeptidase activity
GO:0030145 manganese ion binding
GO:0046872 metal ion binding
GO:0070006 metalloaminopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0019538 protein metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ome, PDBe:6ome, PDBj:6ome
PDBsum6ome
PubMed
UniProtO84049|AMPA_CHLTR Probable cytosol aminopeptidase (Gene Name=pepA)

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