Structure of PDB 6ogz Chain A Binding Site BS01

Receptor Information
>6ogz Chain A (length=1082) Species: 28875 (Rotavirus A) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKYNLILSEYLSFIYNSQSAVQIPIYYSSNSELENRCIEFHSKCLENSKN
GLSLKKLFVEYSDVIENATLLSILSYSYDKYNAVERKLVKYAKGKPLEAD
LTVNELDYENNKITSELFPTAEEYTDLLMDPAILTSLSSNLNAVMFWLEK
HENDVAEKLKIYKRRLDLFTIVASTVNKYGVPRHNAKYRYEYEVMKDKPY
YLVTWANSSIEMLMSVFSHEDYLIARELIVLSYSNRSTLAKLVSSPMSIL
VALVDINGTFITNEELELEFSNKYVRAIVPDQTFDELKQMLDNMRKAGLT
DIPKMIQDWLVDCSIEKFPLMAKIYSWSFHVGFRKQKMLDAALDQLKTEY
TEDVDDEMYREYTMLIRDEVVKMLEEPVKHDDHLLQDSELAGLLSMSSAS
NGESRQLKFGRKTIFSTKKNMHVMDDMANGRYTPGIIPPVNVDKPIPLGR
RDVPGRRTRIIFILPYEYFIAQHAVVEKMLIYAKHTREYAEFYSQSNQLL
SYGDVTRFLSNNSMVLYTDVSQWDSSQHNTQPFRKGIIMGLDMLANMTND
ARVIQTLNLYKQTQINLMDSYVQIPDGNVIKKIQYGAVASGEKQTKAANS
IANLALIKTVLSRISNKYSFATKIIRVDGDDNYAVLQFNTEVTKQMVQDV
SNDVRETYARMNTKVKALVSTVGIEIAKRYIAGGKIFFRAGINLLNNEKK
GQSTQWDQAAVLYSNYIVNRLRGFETDREFILTKIMQMTSVAITGSLRLF
PSERVLTTNSTFKVFDSEDFIIEYGTTDDEVYIQRAFMSLSSQKSGIADE
IAASSTFKNYVSRLSEQLLFSKNNIVSRGIALTEKAKLNSYAPISLEKRR
AQISALLTMLQKPVTFKSSKITINDILRDIKPFFTVNEAHLPIQYQKFMP
TLPDNVQYIIQCIGSRTYQIEDDGSKSAISRLISKYSVYKPSIEELYKVI
SLHENEIQLYLISLGIPKIDADTYVGSKIYSQDKYRILESYVYNLLSINY
GCYQLFDFNSPDLEKLIRIPFKGKIPAVTFILHLYAKLEVINHAIKNGSW
ISLFCNYPKSEMIKLWKKMWNITSLRSPYTNA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6ogz In situ structures of rotavirus polymerase in action and mechanism of mRNA transcription and release.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		I482 D632 K679 R690 I693 R723 A837 K838 S841 R932 I944 Q983
Binding residue
(residue number reindexed from 1)		I481 D631 K678 R689 I692 R722 A836 K837 S840 R931 I943 Q982
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription
GO:0006351 DNA-templated transcription
GO:0019079 viral genome replication
Cellular Component
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ogz, PDBe:6ogz, PDBj:6ogz
PDBsum6ogz
PubMed31101900
UniProtG0YZJ9

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