Structure of PDB 6ogy Chain A Binding Site BS01

Receptor Information
>6ogy Chain A (length=1053) Species: 28875 (Rotavirus A) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKYNLILSEYLSFIYNSQSAVQIPIYYSSNSENATLLSILSYSYDKYNAV
ERKLVKYAKGKPLEADLTVNELDYENNKITSELFPTAEEYTDLLMDPAIL
TSLSSNLNAVMFWLEKHENDVAEKLKIYKRRLDLFTIVASTVNKYGVPRH
NAKYRYEYEVMKDKPYYLVTWANSSIEMLMSVFSHEDYLIARELIVLSYS
NRSTLAKLVSSPMSILVALVDINGTFITNEELELEFSNKYVRAIVPDQTF
DELKQMLDNMRKAGLTDIPKMIQDWLVDCSIEKFPLMAKIYSWSFHVGFR
KQKMLDAALDQLKTEYTEDVDDEMYREYTMLIRDEVVKMLEEPVKHDDHL
LQDSELAGLLSMSSASNGESRQLKFGRKTIFSTKKNMHVMDDMANGRYTP
GIIPPVNVDKPIPLGRRDVPGRRTRIIFILPYEYFIAQHAVVEKMLIYAK
HTREYAEFYSQSNQLLSYGDVTRFLSNNSMVLYTDVSQWDSSQHNTQPFR
KGIIMGLDMLANMTNDARVIQTLNLYKQTQINLMDSYVQIPDGNVIKKIQ
YGAVASGEKQTKAANSIANLALIKTVLSRISNKYSFATKIIRVDGDDNYA
VLQFNTEVTKQMVQDVSNDVRETYARMNTKVKALVSTVGIEIAKRYIAGG
KIFFRAGINLLNNEKKGQSTQWDQAAVLYSNYIVNRLRGFETDREFILTK
IMQMTSVAITGSLRLFPSERVLTTNSTFKVFDSEDFIIEYGTTDDEVYIQ
RAFMSLSSQKSGIADEIAASSTFKNYVSRLSEQLLFSKNNIVSRGIALTE
KAKLNSYAPISLEKRRAQISALLTMLQKPVTFKSSKITINDILRDIKPFF
TVNEAHLPIQYQKFMPTLPDNVQYIIQCIGSRTYQIEDDGSKSAISRLIS
KYSVYKPSIEELYKVISLHENEIQLYLISLGIPKIDADTYVGSKIYSQDK
YRILESYVYNLLSINYGCYQLFDFNSPDLEKLIRIPFKGKIPAVTFILHL
YAKLEVINHAIKNGSWISLFCNYPKSEMIKLWKKMWNITSLRSPYTNANF
FQD
Ligand information
Receptor-Ligand Complex Structure
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PDB6ogy In situ structures of rotavirus polymerase in action and mechanism of mRNA transcription and release.
Resolution3.4 Å
Binding residue
(original residue number in PDB)
Y16 D80 K81 Y82 S137 S140 R184 H185 Y189 Q738 R749
Binding residue
(residue number reindexed from 1)
Y15 D45 K46 Y47 S102 S105 R149 H150 Y154 Q703 R714
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription
GO:0006351 DNA-templated transcription
GO:0019079 viral genome replication
Cellular Component
GO:0044423 virion component

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6ogy, PDBe:6ogy, PDBj:6ogy
PDBsum6ogy
PubMed31101900
UniProtG0YZJ9

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