Structure of PDB 6o9b Chain A Binding Site BS01
Receptor Information
>6o9b Chain A (length=278) Species:
9606
(Homo sapiens) [
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SGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRA
PWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMY
GCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEA
AHEAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEA
TLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVV
PSGEEQRYTCHVQHEGLPKPLTLRWELS
Ligand information
>6o9b Chain C (length=9) Species:
9606
(Homo sapiens) [
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TTAPSLSGK
Receptor-Ligand Complex Structure
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PDB
6o9b
An engineered antibody fragment targeting mutant beta-catenin via major histocompatibility complex I neoantigen presentation.
Resolution
2.2 Å
Binding residue
(original residue number in PDB)
Y7 E63 N66 T73 D77 Y84 Y99 R114 D116 T143 K146 W147 E152 Q155 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y8 E64 N67 T74 D78 Y85 Y100 R115 D117 T144 K147 W148 E153 Q156 Y160 W168 Y172
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6o9b
,
PDBe:6o9b
,
PDBj:6o9b
PDBsum
6o9b
PubMed
31690625
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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