Structure of PDB 6o7i Chain A Binding Site BS01

Receptor Information
>6o7i Chain A (length=741) Species: 523850 (Thermococcus onnurineus NA1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EIDELTALGGLLHDIGKPVQRAGLYDHSTQGARFLRDLAENTGRAEYELL
SLFSEFHHKGHMKNDELMIRRIKELSPERFGLTMEDVLNALWIVYEADNL
ASGPLYSVFNPGKAYPWAELDFEKELPVPGDRSQDYRELVKRLWEELSKA
KLRSDRLLPVLEKYLTFVSSVTSEGNIISLYDHMRMTSAIALAMLRAGCT
AEDVRSGRCRKEKRFLLIEGDFSGIQDFIYRVSGKGTLKYLRARSAYLEL
IGWDVVLEILSRLGLTRANVVFNAGGHFMIIAQNTPDAVKELEEIRAKAV
EWLYREFESDLYLAIEWEPVSGREFGREGGKNLFAEARKRLKHKLTVRKL
KRFGEIKGLFEHGHTERLAECPVCGRELPEGKLEPSASDPETKVCPTCNR
LVSLGGNLPKLLGFGRTAKNDAGVLVEGPFSGFVPYLQPVGEQILVKNTL
NPGEIPESAQFVPYFVADYFKKDPKGGVATFEELSMASTGTRRLGVMKGD
VDRLGEFFSSMDSPSKLATASRFMDYFFKGYIGAIIEGKFGYIIGDVPSL
RDWPEEPDIVVVYAGGDAFFIVGAWDQIFELAFRVRRAFNAYTGGKLTLS
VGLGYFDERTPIYRMADVVSERLDTAKDEGRNRVFVVGRSRPLSYEWNHY
EELWRTYAPRIYAGNGRLKGKLESKKGLLWKLLEIRELYVRDPNDVRWAY
LTAYLLGRLVGIDTKAVERKEPQPVYWVDGVLKIVLMAVRR
Ligand information
Receptor-Ligand Complex Structure
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PDB6o7i Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		R630 S701 R777
Binding residue
(residue number reindexed from 1)		R609 S674 R741
Enzymatic activity
Enzyme Commision number 2.7.7.-
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016740 transferase activity
GO:0042802 identical protein binding
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:6o7i, PDBe:6o7i, PDBj:6o7i
PDBsum6o7i
PubMed31326272
UniProtB6YWB8|CAS10_THEON CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A) (Gene Name=csm1)

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