Structure of PDB 6o7b Chain A Binding Site BS01

Receptor Information
>6o7b Chain A (length=703) Species: 523850 (Thermococcus onnurineus NA1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEIDELTALGGLLHDIGKPVQRAGLYSGDHSTQGARFLRDLAENTGRAEY
ELLSLFSENDELMIRRIKELSPERFGLTMEDVLNALWIVYEADNLASPQA
SRPLYSVFNPGKAYPWAELDFEKELPVPGDVFSIRSQDYRELVKRLWEEL
SKAKLRSDRLLPVLEKYLTFVSSVTSEGNIISLYDHMRMTSAIALAMLRA
GCTAGRCRKEKRFLLIEGDFSGIQDFIYRVSTLKYLRARSAYLELIGWDV
VLEILSRLGLTRANVVFNAGGHFMIIAQNTPDAVKELEEIRAKAVEWLYR
EFESDLYLAIEWEPVSGREFGREGNLFAEARKRLKHKLTVRKLKRFGEIK
GLFECNRLVSLLLGFGRTAKNDAGVLVEGPFSGFVPYLQGGRPVGEQILV
KNTLNPGEIPESAQFVPYFVADYFKKDPKGGVATFEELSMASTGTRRLGV
MKGDVDRLGEFFSSMDSPSKLATASRFMDYFFKGYIGAIIEGKFGYIIGD
VPSLRDWPEEPDIVVVYAGGDAFFIVGAWDQIFELAFRVRRAFNAYTGGK
LTLSVGLGYFDERTPIYRMADVVSERLDTAKDEGRNRVFVVGRSRPLDGK
HKLSYEWNHYEELWRTYAPRIYAGNGRLKGKLESKKGLLWKLLEIRELYV
RDPNDVRWAYLTAYLLDLFPELVGIDTKAVERKEPQPVYWVDGVLKIVLM
AVR
Ligand information
Receptor-Ligand Complex Structure
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PDB6o7b Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		Y626 F627 R635 E642 R643 T646 D649 R660 R662
Binding residue
(residue number reindexed from 1)		Y559 F560 R568 E575 R576 T579 D582 R593 R595
Enzymatic activity
Enzyme Commision number 2.7.7.-
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016740 transferase activity
GO:0042802 identical protein binding
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:6o7b, PDBe:6o7b, PDBj:6o7b
PDBsum6o7b
PubMed31326272
UniProtB6YWB8|CAS10_THEON CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A) (Gene Name=csm1)

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