Structure of PDB 6nu9 Chain A Binding Site BS01

Receptor Information
>6nu9 Chain A (length=168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ISDISGSYVVPGTALQPLYQALDLPAEIVARAGRLTATVKVSQVDGRIDC
ETLLGNKTFRTSFVDGAVLETNHNLSFDASQSTMAAGPFSLTYAASAAGL
EVRYVAAGLDHRAVFAPGVSPRSAPGEVTAFCSALYRFNREAQRLNFWFH
PEGLLGPFAPFSPGHVWE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6nu9 Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6nu9 First Crystal Structure of a Nonstructural Hepatitis E Viral Protein Identifies a Putative Novel Zinc-Binding Protein.
Resolution1.761 Å
Binding residue
(original residue number in PDB)		H164 E166
Binding residue
(residue number reindexed from 1)		H150 E152
Annotation score1
Enzymatic activity
Enzyme Commision number 2.1.1.-
2.7.7.-
2.7.7.48: RNA-directed RNA polymerase.
3.4.-.-
3.6.4.-
Gene Ontology
Biological Process
GO:0019082 viral protein processing

View graph for
Biological Process
External links
PDB RCSB:6nu9, PDBe:6nu9, PDBj:6nu9
PDBsum6nu9
PubMed31019049
UniProtP33424|POLN_HEVPA Non-structural polyprotein pORF1 (Gene Name=ORF1)

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