Structure of PDB 6nsr Chain A Binding Site BS01

Receptor Information

>6nsr Chain A (length=192) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GRPRAFDRDTALQRAMDVFWVRGYEGASLAALTEAMEIRPPSLYAAFGSK
EGLFREALAHYLGQHGRYRRDVLDGAPSAREGVAELLRETVARFTSDEFP
RGCLVVLAALTGTPESEAVRDALSAERGESIRLFRERMRRGIADGDLAAD
TDMEELATFYATVLFGLSVQAKDRVPRERLLAVVERALRAWP

Ligand information

>6nsr Chain C (length=26) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ttatttgtatcgatcactataaattt

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6nsr TetR family transcriptional regulator CifR C99T-C181R cysteine mutant complexed with 26bp double-strand operator DNA and apo-CifR C99T-C181R
Resolution	3.0 Å
Binding residue (original residue number in PDB)	G5 R6 A9 F10 R43 P45 S46
Binding residue (residue number reindexed from 1)	G1 R2 A5 F6 R39 P41 S42

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000976	transcription cis-regulatory region binding
GO:0001217	DNA-binding transcription repressor activity
GO:0003677	DNA binding

	Biological Process
GO:0009889	regulation of biosynthetic process
GO:0045892	negative regulation of DNA-templated transcription
GO:0080090	regulation of primary metabolic process

	Cellular Component
GO:0032993	protein-DNA complex

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External links

PDB	RCSB:6nsr, PDBe:6nsr, PDBj:6nsr
PDBsum	6nsr
PubMed
UniProt	Q9HZR6

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