Structure of PDB 6nn6 Chain A Binding Site BS01

Receptor Information
>6nn6 Chain A (length=97) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
Ligand information
>6nn6 Chain I (length=145) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcagaatcccggtgccgaggccgctcaattggtcgtagacagctctagc
accgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgccaaggg
gattactccctagtctccaggcacgtgtcagatatatacatcgat
Receptor-Ligand Complex Structure
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PDB6nn6 Structural Basis for Recognition of Ubiquitylated Nucleosome by Dot1L Methyltransferase.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		H39 R40 Y41 R42 T45 R63 R72 F84 S86 T118
Binding residue
(residue number reindexed from 1)		H2 R3 Y4 R5 T8 R26 R35 F47 S49 T81
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6nn6, PDBe:6nn6, PDBj:6nn6
PDBsum6nn6
PubMed30759380
UniProtP84233|H32_XENLA Histone H3.2

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