Structure of PDB 6nj9 Chain A Binding Site BS01

Receptor Information
>6nj9 Chain A (length=99) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVKALQEASEAYLVALFEDTNLCAIHAKRVTIKPKDIQLARRIRGERA
Ligand information
>6nj9 Chain I (length=146) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tcgagaatcccggtgccgaggccgctcaattggtcgtagacagctctagc
accgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgccaaggg
gattactccctagtctccaggcacgtgtcagatatatacatccgat
Receptor-Ligand Complex Structure
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PDB6nj9 Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
Resolution2.96 Å
Binding residue
(original residue number in PDB)		R40 Y41 G44 V46 R49 K64 L65
Binding residue
(residue number reindexed from 1)		R4 Y5 G8 V10 R13 K28 L29
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6nj9, PDBe:6nj9, PDBj:6nj9
PDBsum6nj9
PubMed30765112
UniProtP84233|H32_XENLA Histone H3.2

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