Structure of PDB 6nbj Chain A Binding Site BS01

Receptor Information

>6nbj Chain A (length=378) Species: 559292 (Saccharomyces cerevisiae S288C)

RKGYKVLAIETSCDDTCVSVLDRFSKSAAPNVLANLKDTLDSIDEGGIIP
TKAHIHHQARIGPLTERALIESNAREGIDLICVTRGPGMPGSLSGGLDFA
KGLAVAWNKPLIGVHHMLGHLLIPRMGTNGKVPQFPFVSLLVSGGHTTFV
LSRAIDDHEILCDTIDIAVGDSLDKCGRELGFKGTMIAREMEKFINQDIN
DQDFALKLEMPSPLKNSASKRNMLSFSFSAFITALRTNLTKLGKTEIQEL
PEREIRSIAYQVQESVFDHIINKLKHVLKSQPEKFKNVREFVCSGGVSSN
QRLRTKLETELGTLNSTSFFNFYYPPMDLCSDNSIMIGWAGIEIWESLRL
VSDLDICPIRQWPLNDLLSVDGWRTDQL

Ligand information

>6nbj Chain C (length=4)

cccc

....

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6nbj Structure of Saccharomyces cerevisiae mitochondrial Qri7 in complex with AMP.
• Resolution: 2.94 Å
• Binding residue (original residue number in PDB): K81 H83 I84 P119 G120
• Binding residue (residue number reindexed from 1): K52 H54 I55 P90 G91

Enzymatic activity

• Enzyme Commision number: 2.3.1.234: N(6)-L-threonylcarbamoyladenine synthase.

Gene Ontology

Molecular Function

• GO:0000049 tRNA binding
• GO:0008252 nucleotidase activity
• GO:0008270 zinc ion binding
• GO:0016746 acyltransferase activity
• GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
• GO:0046872 metal ion binding
• GO:0061711 N(6)-L-threonylcarbamoyladenine synthase activity

Biological Process

• GO:0002949 tRNA threonylcarbamoyladenosine modification
• GO:0006400 tRNA modification
• GO:0008033 tRNA processing
• GO:0070525 tRNA threonylcarbamoyladenosine metabolic process
• GO:0072670 mitochondrial tRNA threonylcarbamoyladenosine modification

Cellular Component

• GO:0005739 mitochondrion
• GO:0005759 mitochondrial matrix

External links

• PDB: RCSB:6nbj, PDBe:6nbj, PDBj:6nbj
• PDBsum: 6nbj
• UniProt: P43122|QRI7_YEAST tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial (Gene Name=QRI7)