Structure of PDB 6n9w Chain A Binding Site BS01

Receptor Information
>6n9w Chain A (length=496) Species: 10760 (Escherichia phage T7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VFLYHIPCDNCGSSDGNSLFSDGHTFCYVCEKWTAMTYNVWNFGESNGRY
SALTARGISKETCQKAGYWIAKVDGVMYQVADYRDQNGNIVSQKVRDKDK
NFKTTGSHKSDALFGKHLWNGGKKIVVTEGEIDMLTVMELQDCKYPVVSL
GHGASAAKKTCAANYEYFDQFEQIILMFDMAAQVLPAGKVRVAVLPCKDA
NECHLNGHDREIMEQVWNAGPWIPDGVVSALSLRERIREHLSVGLLFSGC
TGINDKTLGARGGEVIMVTSGSGMGKSTFVRQQALQWGTAMGKKVGLAML
QESVEETAEDLIGLHNRVRLRQSDSLKREIIENGKFDQWFDELFGNDTFH
LYDSTDRLLAKLAYMRSGLGCDVIILDHISIVVDERKMIDNLMTKLKGFA
KSTGVVLVVICHLKNPDKGKAHEEGRPVSITDLRGSGALRQLSDTIIALE
RNQQGDMPNLVLVRILKCRFTGDTGIAGYMEYNKETGWLEPSSYSG
Ligand information
>6n9w Chain F (length=17) Species: 10760 (Escherichia phage T7) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GVVSALSLRERIREHLS
Receptor-Ligand Complex Structure
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PDB6n9w Structures and operating principles of the replisome.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		E347 A350 E351 F378 F382 D389 H392 L393
Binding residue
(residue number reindexed from 1)		E305 A308 E309 F336 F340 D347 H350 L351
Enzymatic activity
Enzyme Commision number 2.7.7.-
3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003697 single-stranded DNA binding
GO:0003896 DNA primase activity
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
GO:0043139 5'-3' DNA helicase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006269 DNA replication, synthesis of primer
GO:0032508 DNA duplex unwinding
GO:0039693 viral DNA genome replication
Cellular Component
GO:1990077 primosome complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6n9w, PDBe:6n9w, PDBj:6n9w
PDBsum6n9w
PubMed30679383
UniProtP03692|HELIC_BPT7 DNA helicase/primase (Gene Name=4)

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