Structure of PDB 6n7q Chain A Binding Site BS01

Receptor Information
>6n7q Chain A (length=266) Species: 5833 (Plasmodium falciparum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGII
IETFLKPVATGKDGGFAFPPTNPLISPMTLNGMRDFYKNNEYVKNLDELT
LCSRHAGNMNPDNNSNYKYPAVYDYNDKKCHILYIAAQENNCFRPAKDKL
FENYTYLSKNVVDNWEEVCPRKNLENAKFGLWVDGNCEDIPHVNEFSAND
LFECNKLVFELSASDQPKKSHGKGYNWGNYNRETQKCEIFNVKPTCLINN
SSYIATTALSHPIEVE
Ligand information
>6n7q Chain C (length=13) Species: 5833 (Plasmodium falciparum) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
CWTTRMSPPMQIP
Receptor-Ligand Complex Structure
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PDB6n7q Identification of the Binding Site of Apical Membrane Antigen 1 (AMA1) Inhibitors Using a Paramagnetic Probe.
Resolution2.1 Å
Binding residue
(original residue number in PDB)
F183 T186 G222 N223 M224 N225 P226 Y234 Y236
Binding residue
(residue number reindexed from 1)
F68 T71 G107 N108 M109 N110 P111 Y117 Y119
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:6n7q, PDBe:6n7q, PDBj:6n7q
PDBsum6n7q
PubMed30653832
UniProtQ1PBJ5

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