Structure of PDB 6n2o Chain A Binding Site BS01

Receptor Information
>6n2o Chain A (length=572) Species: 156889 (Magnetococcus marinus MC-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EKKDLIIRVAGEGGEGIISSGDFIAAACARAGLEVYTFKTFPAEIKGGYA
MYQVRASSEKLYCQGDTFDVFCAFNGEAYEQNKDKIKPGTAFVYDYPGGD
FEPDEIPEGVFAYPIPMSQTAKEMKSYRSKNMVALGALSELFNISENTLK
EVLSDKFGKKGEEVLAFNLEAFDKGKALAKALTKADPFRVADPQEPKDVI
IMAGNDAVGLGGILGGLEFFSAYPITPATEVAKYVATHLPKCGGDLVQAE
DEIASIAQVLGASYAGKKSMTATSGPGLALMSEMLGMAHMSETPCLVVDV
QRGGPSTGLPTKHEQSDLFLAIHGGHGDSPRIVLSVEDVKDCISMTVDGL
NLAEKYQAPVIVLSDGSLAFSTQTIPRPKPEDFTIINRKTWDGQGTYKRY
ELTEDNISPMAAPGTPNAKHIATGLEHGETGAPNYSPANHELMHRKRFNK
QNSVLDFYKNMEVEGVEGEADVGIITWGSTIGVVREAMQRLTAEGLKVKA
MYPKLLWPMPVADYDAFGATCKKVIVPEVNFQGQLSHFIRAETSIKPIPY
TICGGLPFTPEMIVNRVKEEIQ
Ligand information
Ligand IDAKG
InChIInChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
InChIKeyKPGXRSRHYNQIFN-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=C(O)C(=O)CCC(=O)O
OpenEye OEToolkits 1.7.6C(CC(=O)O)C(=O)C(=O)O
CACTVS 3.385OC(=O)CCC(=O)C(O)=O
FormulaC5 H6 O5
Name2-OXOGLUTARIC ACID
ChEMBLCHEMBL1686
DrugBankDB08845
ZINCZINC000001532519
PDB chain6n2o Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6n2o A reverse TCA cycle 2-oxoacid:ferredoxin oxidoreductase that makes C-C bonds from CO2.
Resolution2.824 Å
Binding residue
(original residue number in PDB)		T227 R303
Binding residue
(residue number reindexed from 1)		T226 R302
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors
Biological Process
GO:0006979 response to oxidative stress

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:6n2o, PDBe:6n2o, PDBj:6n2o
PDBsum6n2o
PubMed31080943
UniProtA0L8G4

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