Structure of PDB 6mzi Chain A Binding Site BS01

Receptor Information
>6mzi Chain A (length=267) Species: 42789 (enterovirus D68) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IESIIKTATDTVKSELGVVPSLNAVETGATSNTEPEEAIQTRTVINQHGV
SETLVENFLSRAALVSKRSFEYKDKNFFKWTINTRSFVQLRRKLELFTYL
RFDAEITILTTVAVGLPDLTLQAMFVPTGALTPEKQDSFHWQSGSNASVF
FKISDPPARITIPFMCINSAYSVFYDGFAGFEKNGLYGINPADTIGNLCV
RIVNEHQPVGFTVTVRVYMKPKHIKAWAPRPPRTLPYMSIANANYKGKER
APNALSAIIGNRDSVKT
Ligand information
>6mzi Chain D (length=28) Species: 42789 (enterovirus D68) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
NFYKDSYAASASKQDFSQDPSKFTEPVV
Receptor-Ligand Complex Structure
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PDB6mzi Molecular basis for the acid-initiated uncoating of human enterovirus D68.
Resolution3.46 Å
Binding residue
(original residue number in PDB)
E2 S3 I5 A33 T34 E60 N61 D116 T183 P185 K244 H245 P251
Binding residue
(residue number reindexed from 1)
E2 S3 I5 A29 T30 E56 N57 D103 T161 P163 K222 H223 P229
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
External links