Structure of PDB 6mzi Chain A Binding Site BS01
Receptor Information
>6mzi Chain A (length=267) Species:
42789
(enterovirus D68) [
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IESIIKTATDTVKSELGVVPSLNAVETGATSNTEPEEAIQTRTVINQHGV
SETLVENFLSRAALVSKRSFEYKDKNFFKWTINTRSFVQLRRKLELFTYL
RFDAEITILTTVAVGLPDLTLQAMFVPTGALTPEKQDSFHWQSGSNASVF
FKISDPPARITIPFMCINSAYSVFYDGFAGFEKNGLYGINPADTIGNLCV
RIVNEHQPVGFTVTVRVYMKPKHIKAWAPRPPRTLPYMSIANANYKGKER
APNALSAIIGNRDSVKT
Ligand information
>6mzi Chain D (length=28) Species:
42789
(enterovirus D68) [
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NFYKDSYAASASKQDFSQDPSKFTEPVV
Receptor-Ligand Complex Structure
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PDB
6mzi
Molecular basis for the acid-initiated uncoating of human enterovirus D68.
Resolution
3.46 Å
Binding residue
(original residue number in PDB)
E2 S3 I5 A33 T34 E60 N61 D116 T183 P185 K244 H245 P251
Binding residue
(residue number reindexed from 1)
E2 S3 I5 A29 T30 E56 N57 D103 T161 P163 K222 H223 P229
Enzymatic activity
Enzyme Commision number
2.7.7.48
: RNA-directed RNA polymerase.
3.4.22.28
: picornain 3C.
3.4.22.29
: picornain 2A.
3.6.1.15
: nucleoside-triphosphate phosphatase.
External links
PDB
RCSB:6mzi
,
PDBe:6mzi
,
PDBj:6mzi
PDBsum
6mzi
PubMed
30530701
UniProt
A0A097BW12
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