Structure of PDB 6mx9 Chain A Binding Site BS01

Receptor Information

>6mx9 Chain A (length=129) Species: 9031 (Gallus gallus)

KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGS
TDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVS
DGNGMNAWVAWRNRCKGTDVQAWIRGCRL

Ligand information

• Ligand ID: K5V
• InChI: InChI=1S/C6H7NO/c7-5-2-1-3-6(8)4-5/h1-4,8H,7H2
• InChIKey: CWLKGDAVCFYWJK-UHFFFAOYSA-N
• SMILES:
  OpenEye OEToolkits 2.0.6: c1cc(cc(c1)O)N
  ACDLabs 12.01: c1(cc(N)ccc1)O
  CACTVS 3.385: Nc1cccc(O)c1
• Formula: C6 H7 N O
• Name: 3-aminophenol
• ChEMBL: CHEMBL269755
• ZINC: ZINC000000157527
• PDB chain: 6mx9 Chain A Residue 211

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6mx9 A simple technique to improve microcrystals using gel exclusion of nucleation inducing elements
• Resolution: 1.35 Å
• Binding residue (original residue number in PDB): G71 S72
• Binding residue (residue number reindexed from 1): G71 S72
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): E35 N46 D48 S50 D52 N59
• Catalytic site (residue number reindexed from 1): E35 N46 D48 S50 D52 N59
• Enzyme Commision number: 3.2.1.17: lysozyme.

Gene Ontology

Molecular Function

• GO:0003796 lysozyme activity
• GO:0005515 protein binding
• GO:0016231 beta-N-acetylglucosaminidase activity
• GO:0016798 hydrolase activity, acting on glycosyl bonds
• GO:0042802 identical protein binding

Biological Process

• GO:0016998 cell wall macromolecule catabolic process
• GO:0031640 killing of cells of another organism
• GO:0042742 defense response to bacterium
• GO:0050829 defense response to Gram-negative bacterium
• GO:0050830 defense response to Gram-positive bacterium

Cellular Component

• GO:0005576 extracellular region
• GO:0005615 extracellular space
• GO:0005737 cytoplasm
• GO:0005783 endoplasmic reticulum

External links

• PDB: RCSB:6mx9, PDBe:6mx9, PDBj:6mx9
• PDBsum: 6mx9
• UniProt: P00698|LYSC_CHICK Lysozyme C (Gene Name=LYZ)