Structure of PDB 6mv3 Chain A Binding Site BS01

Receptor Information
>6mv3 Chain A (length=125) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQ
NPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRSMKDDSKGKFKRPTLRR
VRISADAMMQALLGARAKGHHHHHH
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6mv3 Chain A Residue 200 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6mv3 Structural Changes Induced by the Binding of the Calcium Desensitizer W7 to Cardiac Troponin.
ResolutionN/A
Binding residue
(original residue number in PDB)		D65 D67 S69 T71 E76
Binding residue
(residue number reindexed from 1)		D65 D67 S69 T71 E76
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Cellular Component
GO:0005861 troponin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:6mv3, PDBe:6mv3, PDBj:6mv3
PDBsum6mv3
PubMed30376637
UniProtP19429;
P63316|TNNC1_HUMAN Troponin C, slow skeletal and cardiac muscles (Gene Name=TNNC1)

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