Structure of PDB 6mup Chain A Binding Site BS01

Receptor Information
>6mup Chain A (length=102) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HQHSRRRQGWLKEIRKLQKSTHLLIRKLPFSRLAREICVKFTRGVDFNWQ
AQALLALQEAAEAFLVHLFEDAYLLTLHAGRVTLFPKDVQLARRIRGLEE
GL
Ligand information
>6mup Chain I (length=147) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcaaatatccacctgcagattctaccaaaagtgtatttggaaactgctc
catcaaaaggcatgttcagctctgtgagtgaaactccatcatcacaaaga
atattctgagaatgcttccgtttgccttttatatgaacttcctcgat
Receptor-Ligand Complex Structure
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PDB6mup Structure of the Human Core Centromeric Nucleosome Complex.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
R72 N85 W86 Q87 R118 V119
Binding residue
(residue number reindexed from 1)
R35 N48 W49 Q50 R81 V82
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:6mup, PDBe:6mup, PDBj:6mup
PDBsum6mup
PubMed31353180
UniProtP49450|CENPA_HUMAN Histone H3-like centromeric protein A (Gene Name=CENPA)

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