Structure of PDB 6mu0 Chain A Binding Site BS01

Receptor Information
>6mu0 Chain A (length=152) Species: 243273 (Mycoplasmoides genitalium G37) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMSFNIFIASDHTGLTLKKIISEHLKTKQFNVVDLGPNYFDANDDYPDFA
FLVADKVKKNSDKDLGILICGTGVGVCMAANKVKGVLAALVVSEKTAALA
RQHDNANVLCLSSRFVTDSENIKIVDDFLKANFEGGRHQRRIDKIIRYEK
ET
Ligand information
Ligand ID5RP
InChIInChI=1S/C5H11O8P/c6-1-3(7)5(9)4(8)2-13-14(10,11)12/h4-6,8-9H,1-2H2,(H2,10,11,12)/t4-,5+/m1/s1
InChIKeyFNZLKVNUWIIPSJ-UHNVWZDZSA-N
SMILES
SoftwareSMILES
CACTVS 3.341OCC(=O)[C@H](O)[C@H](O)CO[P](O)(O)=O
OpenEye OEToolkits 1.5.0C(C(C(C(=O)CO)O)O)OP(=O)(O)O
CACTVS 3.341OCC(=O)[CH](O)[CH](O)CO[P](O)(O)=O
ACDLabs 10.04O=P(O)(O)OCC(O)C(O)C(=O)CO
OpenEye OEToolkits 1.5.0C([C@H]([C@H](C(=O)CO)O)O)OP(=O)(O)O
FormulaC5 H11 O8 P
NameRIBULOSE-5-PHOSPHATE
ChEMBL
DrugBank
ZINCZINC000001532567
PDB chain6mu0 Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6mu0 Crystal Structure of Ribose-5-phosphate Isomerase B from Mycoplasma genitalium with bound Ribulose-5-phosphate
Resolution1.1 Å
Binding residue
(original residue number in PDB)		D10 H11 Y45 A69 G70 T71 G74 R113
Binding residue
(residue number reindexed from 1)		D11 H12 Y46 A70 G71 T72 G75 R114
Annotation score5
Enzymatic activity
Enzyme Commision number 5.3.1.6: ribose-5-phosphate isomerase.
Gene Ontology
Molecular Function
GO:0004751 ribose-5-phosphate isomerase activity
GO:0016853 isomerase activity
GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006098 pentose-phosphate shunt
GO:0009052 pentose-phosphate shunt, non-oxidative branch
GO:0019316 D-allose catabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6mu0, PDBe:6mu0, PDBj:6mu0
PDBsum6mu0
PubMed
UniProtP47636|RPIB_MYCGE Probable ribose-5-phosphate isomerase B (Gene Name=rpiB)

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