Structure of PDB 6mf4 Chain A Binding Site BS01

Receptor Information
>6mf4 Chain A (length=235) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LIATSTNVIKSEISLRILASECHLTLNGIVEAEAQYKMGGLPKSRLPKIK
HPMIVTKWVDYSNKHGFSYQLSTEDIGVLFNNGTTVLRLADAEEFWYISY
DDREGWVASHYLLSEKPRELSRHLEVVDFFAKYMKTFGREEYHKDDVFLR
RYTRYKPFVMFELSDGTFQFNFKDHHKMAISDGGKLVTYISPSHESTTYP
LVEVLKYGEIPGYPESNFREKLTLIKEGLKQKSTI
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6mf4 Chain A Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6mf4 Distinct surfaces on Cdc5/PLK Polo-box domain orchestrate combinatorial substrate recognition during cell division.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		E553 H569 H609
Binding residue
(residue number reindexed from 1)		E94 H110 H143
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.11.21: polo kinase.
External links
PDB RCSB:6mf4, PDBe:6mf4, PDBj:6mf4
PDBsum6mf4
PubMed32099015
UniProtP32562|CDC5_YEAST Cell cycle serine/threonine-protein kinase CDC5/MSD2 (Gene Name=CDC5)

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