Structure of PDB 6m90 Chain A Binding Site BS01
Receptor Information
>6m90 Chain A (length=402) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
SMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGM
LWKKLIERMVRTDSLWRGLAERRGWGQYLFPPNSFYRALYPKIIQDIETI
ESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNT
LECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHH
CEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVV
DFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSG
SSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWD
LVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDF
LN
Ligand information
>6m90 Chain C (length=10) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
LDSGIHSGAT
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
6m90
Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction.
Resolution
2.05 Å
Binding residue
(original residue number in PDB)
Y271 R285 S309 S325 L351 K365 N394 R474 Y488 R521 F523
Binding residue
(residue number reindexed from 1)
Y125 R139 S163 S179 L205 K219 N248 R328 Y342 R375 F377
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6m90
,
PDBe:6m90
,
PDBj:6m90
PDBsum
6m90
PubMed
30926793
UniProt
Q9Y297
|FBW1A_HUMAN F-box/WD repeat-containing protein 1A (Gene Name=BTRC)
[
Back to BioLiP
]
