Structure of PDB 6m7k Chain A Binding Site BS01

Receptor Information
>6m7k Chain A (length=318) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HCVKLNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAY
QVEEEIGQAIQSAIAAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKK
LQLDYVDLYIMHYPVPMKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECK
DAGLVKSIGVSNFNHRQLERILNKPGLNYKPVCNQVECHLYLNQRKLLDY
CESKDIVLVAYGALGTQRYKEWVDQNSPVLLNDPVLCDVAKKNKRSPALI
ALRYLIQRGIVPLAQSFKENEMRENLQVFGFQLSPEDMKTLDGLNKNFRY
LPAEFLVDHPEYPFVEEY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6m7k Bacterial cGAS-like enzymes synthesize diverse nucleotide signals.
Resolution1.1 Å
Binding residue
(original residue number in PDB)		Y24 P26 E28 G217 L219 Q222 A253 Q270 E276 E279 N280 L306
Binding residue
(residue number reindexed from 1)		Y19 P21 E23 G212 L214 Q217 A248 Q265 E271 E274 N275 L301
Enzymatic activity
Enzyme Commision number 1.1.1.-
Gene Ontology
Molecular Function
GO:0004033 aldo-keto reductase (NADPH) activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006805 xenobiotic metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6m7k, PDBe:6m7k, PDBj:6m7k
PDBsum6m7k
PubMed30787435
UniProtQ8VC28|AK1CD_MOUSE Aldo-keto reductase family 1 member C13 (Gene Name=Akr1c13)

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