Structure of PDB 6m64 Chain A Binding Site BS01

Receptor Information
>6m64 Chain A (length=203) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLG
LLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQ
RYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTI
RMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCS
EME
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6m64 Structural basis for transcriptional coactivator recognition by SMAD2 in TGF-beta signaling.
Resolution1.45 Å
Binding residue
(original residue number in PDB)
Q388 A391 A392 A395 V398 W448 Q455
Binding residue
(residue number reindexed from 1)
Q124 A127 A128 A131 V134 W184 Q191
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Biological Process
External links
PDB RCSB:6m64, PDBe:6m64, PDBj:6m64
PDBsum6m64
PubMed33323411
UniProtQ15796|SMAD2_HUMAN Mothers against decapentaplegic homolog 2 (Gene Name=SMAD2)

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