Structure of PDB 6m64 Chain A Binding Site BS01
Receptor Information
>6m64 Chain A (length=203) Species:
9606
(Homo sapiens) [
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PVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLG
LLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQ
RYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTI
RMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCS
EME
Ligand information
>6m64 Chain B (length=19) Species:
9606
(Homo sapiens) [
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GPPPAAVEAARQILREAQQ
Receptor-Ligand Complex Structure
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PDB
6m64
Structural basis for transcriptional coactivator recognition by SMAD2 in TGF-beta signaling.
Resolution
1.45 Å
Binding residue
(original residue number in PDB)
Q388 A391 A392 A395 V398 W448 Q455
Binding residue
(residue number reindexed from 1)
Q124 A127 A128 A131 V134 W184 Q191
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0006355
regulation of DNA-templated transcription
View graph for
Biological Process
External links
PDB
RCSB:6m64
,
PDBe:6m64
,
PDBj:6m64
PDBsum
6m64
PubMed
33323411
UniProt
Q15796
|SMAD2_HUMAN Mothers against decapentaplegic homolog 2 (Gene Name=SMAD2)
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