Structure of PDB 6ltu Chain A Binding Site BS01

Receptor Information
>6ltu Chain A (length=1034) Species: 32644 (unidentified) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMSSAIKSYKSVLRPNERKNQLLKSTIQCLEDGSAFFFKMLQGLFGGITP
EIVRFSTEQEKQQQDIALWCAVNWFRPVSQDSLTHTIASDNLVEKFEEYY
GGTASDAIKQYFSASIGESYYWNDCRQQYYDLCRELGVEVSDLTHDLEIL
CREKCLAVATESNQNNSIISVLFGTGEKEDRSVKLRITKKILEAISNLKE
IPKNVAPIQEIILNVAKATKETFRQVYAGNLGAPSTLEKFIAKDGQKEFD
LKKLQTDLKKVIRGKSKERDWCCQEELRSYVEQNTIQYDLWAWGEMFNKA
HTALKIKSTRNYNFAKQRLEQFKEIQSLNNLLVVKKLNDFFDSEFFSGEE
TYTICVHHLGGKDLSKLYKAWEDDPADPENAIVVLCDDLKNNFKKEPIRN
ILRYIFTIRQECSAQDILAAAKYNQQLDRYKSQKANPSVLGNQGFTWTNA
VILPEKAQRNDRPNSLDLRIWLYLKLRHPDGRWKKHHIPFYDTRFFQEIY
AAGNSPVDTCQFRTPRFGYHLPKLTDQTAIRVNKKHVKAAKTEARIRLAI
QQGTLPVSNLKITEISATINSKGQVRIPVKFDVGRQKGTLQIGDRFCGYD
QNQTASHAYSLWEVVKEGQYHKELGCFVRFISSGDIVSITENRGNQFDQL
SYEGLAYPQYADWRKKASKFVSLWQITKKNKKKEIVTVEAKEKFDAICKY
QPRLYKFNKEYAYLLRDIVRGKSLVELQQIRQEIFRFIEQDCGVTRLGSL
SLSTLETVKAVKGIIYSYFSTALNASKNNPISDEQRKEFDPELFALLEKL
ELIRTRKKKQKVERIANSLIQTCLENNIKFIRGEGDLSTTNNATKKKANS
RSMDWLARGVFNKIRQLAPMHNITLFGCGSLYTSHQDPLVHRNPDKAMKC
RWAAIPVKDIGDWVLRKLSQNLRAKNIGTGEYYHQGVKEFLSHYELQDLE
EELLKWRSDRKSNIPCWVLQNRLAEKLGNKEAVVYIPVRGGRIYFATHKV
ATGAVSIVFDQKQVWVCNADHVAAANIALTVKGI
Ligand information
>6ltu Chain B (length=49) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agaaauccgucuuucauugacggaacagagcaagcagggugacauuauu
......<<<<<.......>>>>>..........................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6ltu Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2.
Resolution2.57 Å
Binding residue
(original residue number in PDB)		I5 S7 K9 S10 R13 P14 N15 K18 Y119 K306 S346 E348 R398 R402 R428 K433 N435 P436 N441 Q442 Q457 N459 R461 S464 D466 L467 R468 W470 H486 P488 Y490 D491 T492 R493 R515 L523 T524 D525 A528 I529 R530 V531 K533 K534 H535 V536 K537 A538 K540 R575 T639 E640 N641 R642 N644 Q648 Y651 L654 Y659 W662 Y704 R715 R719 D740 C741 R745 L746 G747 L749 Y765 S766 S769 A774 S775 R805 Q809 E812 R813 N816 T839 N840 N841 K845 N848 S849 M852 Q865 L866 M869
Binding residue
(residue number reindexed from 1)		I6 S8 K10 S11 R14 P15 N16 K19 Y120 K307 S347 E349 R399 R403 R429 K434 N436 P437 N442 Q443 Q458 N460 R462 S465 D467 L468 R469 W471 H487 P489 Y491 D492 T493 R494 R516 L524 T525 D526 A529 I530 R531 V532 K534 K535 H536 V537 K538 A539 K541 R576 T640 E641 N642 R643 N645 Q649 Y652 L655 Y660 W663 Y705 R716 R720 D741 C742 R746 L747 G748 L750 Y766 S767 S770 A775 S776 R806 Q810 E813 R814 N817 T840 N841 N842 K846 N849 S850 M853 Q866 L867 M870
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